年10月28日星期三
一起的第26天
TheRoleofInhibitoryControlintheHospitalizationofChildrenwithSeverePsychiatricDisorders
01第一作者:BrianC.Kavanaugh
02第一单位:布朗大学
03通讯作者:KarenA.Holler
1
Abstract
Objective:Inhibitorycontrolisaheterogeneousdomaininvolvingmultipleinhibitoryprocessesatlevelsofbehavior,attention/cognition,andemotion/motivation.Priorstudieshaveidenti?edanunderlyingroleofinhibitorycontrolinthemanifestationofchildhood-onsetpsychiatricsymptoms.Thisstudyinvestigatedtheinhibitorycontrolabilitiesofchildrenwithinasevere,childhoodpsychiatricsample.
Method:Amedicalchartreviewwasconductedforchildrenwhoreceivedaneuropsychologicalevaluationduringachildren’spsychiatricinpatientprogramhospitalizationfromto.Threemeasuresneurocognitiveofinhibitorycontrol,StroopColor–WordScore,CPT-IICommissionErrors,andWCSTFailuretoMaintainSetwereusedinthepresentstudy.Thepresenceofexternalizingbehaviorsathospitaladmissionwasclassi?edaspoorbehavioral/self-control.
Results:Forty-eightpercentofthesampledisplayedevidenceofinhibitorycontrolimpairmentonneurocognitivemeasures,with40%displayingresponseinhibitionimpairmentandonly5–7%displayinginterferencecontrolimpairment.Similarlyelevatedratesofimpairmentwerefoundinthosechildrenwithoutattentionde?cithyperactivitydisorder(ADHD).Depressivedisorderswereassociatedwithinterferencecontrol,whileADHDwasassociatedwithinterferencecontrolandresponseinhibition.ReceiverOperatingCharacteristicanalysisfoundthatresponseinhibitionpredictedaprolongedhospitalizationinanoldermalessubgroupbutnotintheyoungermalesorfemalessubgroups.
Conclusions:Current?ndingssuggestthatinhibitorycontrolimpairmentsarehighlyprevalentinthechildren’spsychiatricinpatientsettingandassociatedwithspeci?cpsychiatricdisorders,althoughthein?uenceoftheseimpairmentsonsubsequentout